M.A.I.K®

Mobile detection kit for nerve agents

The use of nerve agents in the recent past

The use of nerve agents is a continuous and serious threat with the most recent examples being the use of Sarin in 2013, VX in 2017 and Novichok in 2018 and 2020. Early detection of these substances allows immediate countermeasures to be taken on site (e.g. decontamination or initiation of therapy).

About M.A.I.K®
M.A.I.K® is a mobile and highly sensitive test kit that can easily and quickly be used to detect a surface contamination (e.g. skin) with nerve agents and other cholinesterase inhibitors within a few minutes1. The principle of M.A.I.K® is based on a simple color reaction:
  • A solution remains colorless when the sampled surface contains an AChE-inhibitor (e.g. a nerve agent).
  • The test solution turns yellow if the surface does not contain an AChE-inhibitor.
M.A.I.K® contains the following components:
Component 1: Sampler

Cotton swab for sampling the surface

Component 2: Buffer solution

Maintaining stable reaction conditions

Component 3: Yellow enzyme cap

Contains human AChE

Component 4: Red reagent cap

Activates the color reaction

Working principle

M.A.I.K® is a 4-step-measurement, which can be performed easily and quickly. The principle is based on assessing whether human acetylcholinesterase, which is a component of M.A.I.K®, is either still active or inhibited after a surface has been sampled.

  1. Wipe the surface area with the sampler
  2. Put the sampler into the sample tube
  3. Screw the yellow enzyme cap onto the tube and shake the tube
  4. Screw the red reagent cap onto the tube and shake the tube
Training video
Externer Link zu vimeo.com
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Contact
Dr. Jürgen Maurer Head of Productmanagement in vitro diagnostics Phone: +49 6251 1083-327 Fax: +49 6251 1083-116 j.maurer@koehler-chemie.de

M.A.I.K®

A mobile and generic test based on the inhibition of human acetylcholinesterase (AChE)

Easily detect a surface contamination
(e.g. skin) with nerve agents and other AChE-inhibitors within 3 minutes

Highly sensitive to all human-toxic substances that inhibit AChE

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